Table 2. Dissociation constants (Kd, μM) of selected AQ and AN derivatives with KIT sequences determined by SPR in 10 mM Tris, 50 mM KCl, pH 7.5, 0.025% surfactant P20.
KIT1 | KIT2 | |
---|---|---|
AQ1 | 1.99 ± 0.15 | 1.01 ± 0.15 |
AQ7 | 3.04 ± 0.43 | 2.29 ± 0.28 |
AN6 | 71.5 ± 20.1 | 25.5 ± 4.01 |