Skip to main content
. 2016 Mar 8;7(16):21775–21785. doi: 10.18632/oncotarget.7982

Figure 3. DSGOST inhibits VEGF activation of NF-κB signaling.

Figure 3

(A) NF-κB activity was measured using reporter gene assay (mean ± SD; n = 3). †P = 0.007 versus untreated cells and *P = 0.008 versus only VEGF-treated cells. (B) Left panel, cells were treated with VEGF and DSGOST for the indicated time points and then MMP-9 expression pattern was analyzed. Right panel, cells were treated with VEGF and DSGOST at different concentrations for 24 hours. (C) MMP-9 activity was evaluated via zymography assay. †P = 0.049 versus untreated cells and *P = 0.04 versus only VEGF-treated cells.