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. 2016 Mar 10;7(16):22128–22139. doi: 10.18632/oncotarget.8031

Figure 5. AKT inhibition induces apoptosis in four out of seven T-ALL cell lines.

Figure 5

A panel of T-ALL cell lines were treated with a dose response of four PI3K pathway inhibitors. Annexin V flow cytometry was performed 72 hours post inhibitor treatment. (A–G) mean ± S.E.M. percentage of Annexin V positive cells (n = 2). (H) Mean percentage increase of Annexin V positive cells relative to DMSO control at the following drug concentrations (AZD2014–0.25 μM, AZD5363–1 μM, AZD8186-0.5 μM and AZD8835-0.5 μM). S.E.M = standard error of the mean.