Table 3. Most common hematological malignancies-univariate comparison.
| Acute Leukemia (n=239) | Myeloma (n=69) | Lymphoma (n=53) | p Value | |
|---|---|---|---|---|
| Agea | 52 ± 15 | 60 ± 13d | 55 ± 14e | <0.001 |
| Sex (male)b | 136 (57) | 43 (62) | 32 (59) | 0.69 |
| Charlson scorea | 3.7 ± 1.7e | 5.0 ± 2.4d | 4.4 ± 2.2de | <0.001 |
| PSa | 1.8 ± 1.0 | 2.1 ± 0.9d | 1.9 ± 1.0 | 0.02 |
| Newly diagnosedb | 103 (43) | 12 (17)d | 11 (21)d | <0.0001 |
| Autologous HSCTb | 7 (3) | 24 (35)d | 11 (21)d | <0.0001 |
| Allogeneic HSCTb | 61 (26) | 21 (30) | 15 (28) | 0.70 |
| GVHDb | 31 (13) | 6 (9) | 6 (11) | 0.62 |
| Neutropeniab | 84 (35) | 14 (20)d | 10 (19)d | 0.01 |
| Respiratory distressb | 122 (51) | 28 (41) | 21 (40) | 0.15 |
| SOFA scorea | 8 ± 3 | 8 ± 4 | 8 ± 4 | 0.13 |
| IMVbc | 108 (45) | 31 (45) | 25 (47) | 0.96 |
| RRTbc | 46 (22) | 20 (29) | 11 (21) | 0.22 |
| Vasopressorsbc | 116 (49) | 29 (42) | 35 (66)de | 0.01 |
| SAPS IIa | 55 ± 22 | 62 ± 28 | 57 ± 26 | 0.12 |
| Day-28 mortalityb | 115 (48) | 35 (51) | 21 (40) | 0.44 |
| Day-90 mortalityb | 130 (54) | 42 (61) | 28 (53) | 0.63 |
| 1-year mortalityb | 167 (70) | 50 (72) | 35 (67) | 0.75 |
a
Data expressed as mean ± SD.
b
Data expressed as number (percentage).
c
Within the first 48 hours.
d
p<0.05 compared with leukemia group.
e
p<0.05 compared with myeloma group.
GVHD: graft versus host disease; HSCT: hematopoietic stem cell transplantation; IMV: invasive mechanical ventilation; PS: performance status; RRT: renal replacement therapy.