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. 2016 Mar 18;7(16):22770–22778. doi: 10.18632/oncotarget.8178

Table 4. False-positive report probability values for the associations between neuroblastoma susceptibility and the frequency of genotypes of the LMO1 gene.

Genotype Crude OR (95% CI) Pa Statistical powerb Prior probability
0.25 0.1 0.01 0.001 0.0001
LMO1 rs110419 A > G
AG vs. AA 0.66 (0.47–0.91) 0.012 0.544 0.064 0.169 0.691 0.958 0.996
GG vs. AA 0.57 (0.36–0.90) 0.017 0.284 0.149 0.344 0.852 0.983 0.998
AG/GG vs. AA 0.64 (0.47–0.87) 0.004 0.368 0.033 0.093 0.531 0.919 0.991
AG/GG vs. AA
 > 18 0.54 (0.36–0.81) 0.003 0.140 0.053 0.143 0.647 0.949 0.995
 Males 0.63 (0.42–0.95) 0.027 0.382 0.173 0.386 0.873 0.986 0.999
 Adrenal gland 0.36 (0.20–0.66) 0.001 0.027 0.098 0.247 0.783 0.973 0.997
 Mediastinum 0.59 (0.37–0.92) 0.022 0.285 0.185 0.406 0.882 0.987 0.999
 Stage III + IV 0.57 (0.38–0.85) 0.006 0.215 0.079 0.204 0.738 0.966 0.996
Protective genotypes
 4 vs. 0–3 0.51 (0.32–0.81) 0.005 0.148 0.084 0.215 0.751 0.968 0.997
 > 18 0.45 (0.24–0.87) 0.016 0.141 0.258 0.510 0.92 0.991 0.999
 Males 0.41 (0.23–0.76) 0.004 0.076 0.139 0.326 0.842 0.982 0.998
 Mediastinum 0.27 (0.11–0.68) 0.005 0.040 0.284 0.543 0.929 0.992 0.999
 Stage I + II + 4s 0.43 (0.23–0.84) 0.013 0.115 0.248 0.497 0.916 0.991 0.999
a

Chi-square test was used to calculate the genotype frequency distributions

b

Statistical power was calculated using the number of observations in the subgroup and the OR and P values in this table.