Table 3. Negative binomial regression comparing the counts of total mutations in smokers and non-smokers with lung adenocarcinoma.

		No. of patients	No. of total mutations Median (Range)	p value	Male to female ratio (95% CI ratio)
Non-smoker	Female	128	2 (0–24)	(reference)	1.486 (1.124~1.968)
	Male	71	3 (0–32)	5.52E–03
Smoker	Female	9	2 (1–5)	(reference)	1.496 (0.824–2.733)
	Male	96	3 (0–34)	0.18562