Table 2. Associations between clinical characteristics and MALL expression in colon cancer patients.
| MALL expression | |||
|---|---|---|---|
| Negative | Positive | ||
| Variables | (n = 58) | (n = 145) | P-value |
| Age (y) | 0.319 | ||
| <65 | 20 (34.5) | 61 (42.1) | |
| ≥65 | 38 (65.5) | 84 (57.9) | |
| Gender | 0.151 | ||
| Male | 20 (34.5) | 66 (45.5) | |
| Female | 38 (65.5) | 79 (54.5) | |
| Tumor location | 0.286 | ||
| Right colon | 30 (51.7) | 54 (37.2) | |
| Transverse colon | 5 (8.6) | 14 (9.7) | |
| Left colon | 4 (6.9) | 16 (11.0) | |
| Sigmoid colon | 19 (32.8) | 61 (42.1) | |
| T category | 0.639 | ||
| T1 | 2 (3.4) | 6 (4.1) | |
| T2 | 4 (6.9) | 19 (13.1) | |
| T3 | 23 (39.7) | 53 (36.6) | |
| T4 | 29 (50.0) | 67 (46.2) | |
| N category | 0.008* | ||
| N0 | 28 (48.3) | 80 (55.2) | |
| N1 | 13 (22.4) | 48 (33.1) | |
| N2 | 17 (29.3) | 17 (11.7) | |
| M category | 0.118 | ||
| M0 | 50 (86.2) | 135 (93.1) | |
| M1 | 8 (13.8) | 10 (6.9) | |
| Vessin invasion | 0.027* | ||
| No | 50 (86.2) | 139 (95.9) | |
| Yes | 8 (13.8) | 6 (4.1) | |
| Differentiation | 0.214 | ||
| Well | 29 (50.0) | 70 (48.3) | |
| Moderate | 17 (29.3) | 57 (39.3) | |
| Poor | 12 (20.7) | 18 (12.4) | |
| AJCC stage | 0.351 | ||
| I-II | 27 (46.6) | 78 (53.8) | |
| III-IV | 31 (53.4) | 67 (46.2) | |
| Recurrence and metastasis | 0.016* | ||
| No | 25 (46.3) | 92 (65.2) | |
| Yes | 29 (53.7) | 49 (34.8) | |
| Patient survival | 0.004* | ||
| No | 30 (51.7) | 44 (30.3) | |
| Yes | 28 (48.3) | 101 (69.7) | |
Data are presented as n (%).
P-values are based on the Person χ2 test of Fisher's exact test.
*
P<0.05 indicates a significant difference.
Abbreviation: AJCC, American Joint Committee on Cancer