Table 5. Methylation status of each CpG site.

	Normal tissue		Cancer tissue		P-value
CpG site	Methylated	Unmethylated	Methylated	Unmethylated
First fragment
70	3	27	4	29	0.789
79	3	27	6	27	0.354
92	4	26	6	27	0.599
135	11	19	20	13	0.058
144	12	18	17	16	0.360
193	2	28	5	28	0.285
221	1	29	2	31	0.612
267	6	24	5	28	0.613
290	3	27	4	29	0.789
302	2	28	1	32	0.498
305	1	29	4	29	0.197
323	1	29	3	30	0.349
329	0	30	2	31	0.171
337	3	27	5	28	0.540
Total	52	368	84	378	0.017*
Second fragment
21	2	28	6	24	0.129
39	4	26	7	23	0.317
48	1	29	2	28	0.554
74	1	29	5	25	0.085
77	0	30	1	29	0.313
81	3	27	7	23	0.166
93	3	27	7	23	0.166
121	1	29	7	23	0.023*
123	1	29	7	23	0.023*
125	1	29	9	21	0.006*
129	1	29	7	23	0.023*
137	2	28	8	22	0.038*
139	2	28	6	24	0.129
148	3	27	7	23	0.166
172	1	29	8	22	0.011*
176	1	29	7	23	0.023*
181	1	29	6	24	0.044*
185	1	29	10	20	0.003*
197	2	28	8	22	0.038*
202	2	28	6	24	0.129
206	2	28	9	21	0.020*
209	2	28	7	23	0.071
217	1	29	4	26	0.161
224	0	30	4	26	0.038*
226	1	29	3	27	0.301
248	9	18	11	19	0.792
263	29	1	30	0	0.313
Total	77	730	199	611	<0.001*

^*P<0.05 indicates a significant difference.