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. Author manuscript; available in PMC: 2017 Feb 25.
Published in final edited form as: Nature. 2016 Aug 25;536(7617):484–487. doi: 10.1038/nature19107

Figure 2. Patterns of residue contacts across inactive and active state structures of GPCRs.

Figure 2

a. Contact fingerprinting. For every residue contact, the presence (or absence) of a contact between structurally equivalent residues for all structures is computed. The pattern of presence and absence (filled and empty cells respectively) across multiple structures is termed ‘contact fingerprint’. b. Distribution of the contact fingerprints representing the presence of contacts in the five inactive and five active state structures.