FIGURE 1.

Data mining on public transcriptomic datasets of nasopharyngeal carcinoma. By reappraising the published transcriptomic datasets of nasopharyngeal carcinoma (NPC) versus non-neoplastic nasopharyngeal tissue samples (GSE34573), MTAP is one of the significantly downregulated gene associated with nucleobase, nucleoside, nucleotide, and nucleic acid metabolic process (GO:0006139) in clustering analysis. NPC (blue lines) and non-neoplastic (red lines) tissue specimens were indicated on top of the heatmap, and expression levels of upregulated and downregulated genes were expressed as a series of brightness of red and green colors, respectively, with those unaltered in mRNA expression being coded as black.