Figure 1.

Comparisons of DNA methylation level in malignant, hyperplasia, and benign thyroid tissues. β value was used for estimation of methylation level using the ratio of intensities between methylated and unmethylated alleles, calculating by β value = methylated allele intensity (M)/(unmethylated allele intensity (U) + methylated allele intensity (M) + 100). β value reflects the methylation intensity at each CpG site. β value of 0 to 1 represented signifying percent methylation, from 0% to 100%, respectively, for each CpG site.