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. 2016 Sep 1;11(9):e0162147. doi: 10.1371/journal.pone.0162147

Fig 8. Effect of CYP-epoxygenase inhibitor (MS-PPOH, 1 μM) on coronary reactive hyperemia (CRH) in wild type (WT) mice.

Fig 8

Each WT isolated mouse heart was used as its own control. (A) tracing depicting coronary flow changes at baseline (before CRH) and after CRH was induced by 15-second no-flow ischemia in WT (continuous line) and MS-PPOH-treated WT (dashed line) mice. Repayment volume (B), baseline CF (E), PHF (F), and LVDP (G) decreased (p < 0.05) in MS-PPOH-treated WT versus WT mice. Repayment/debt ratio (C) increased (p < 0.05), whereas repayment duration (D) did not change (p > 0.05) after in MS-PPOH-treated WT versus WT mice. * p < 0.05 versus WT. n = 8.