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. 2016 Sep 1;11(9):e0162147. doi: 10.1371/journal.pone.0162147

Fig 10. Effect of T0070907, PPARγ-antagonist (10 μM) on t-AUCB-enhanced CRH in WT in wild type (WT) mice.

Fig 10

Each WT isolated mouse heart was used as its own control. Inhibition of sEH by t-AUCB enhanced CRH in WT mice. Infusion of t-AUCB (10 μM) increased repayment volume (RV) (p < 0.05, A), repayment/debt ratio (p < 0.05, B), and repayment duration (RD) in WT mice (p < 0.05, C). The t-AUCB-enhanced CRH was attenuated by T0070907. T0070907 decreased RV (A), R/D ratio (B), and RD (C) in t-AUCB-treated-WT mice (p < 0.05). * p < 0.05 versus WT. n = 6.