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. 2016 Sep 1;11(9):e0161472. doi: 10.1371/journal.pone.0161472

Table 2. Baseline Characteristics of CHD cases and non-cases, Normative Aging Study (n = 589).

No CHD (n = 453) CHD (n = 136)
Main Exposure
Totalc Mean ± SD Total Mean ± SD P valuea
Patella lead 449 29.2 ± 18.1 135 32.1 ± 18.8 0.12
Tibia lead 452 20.2 ± 12.5 136 22.6 ± 13.5 0.03
Continuous variables
Age (years) 453 66.1 ± 7.4 136 65.8 ± 6.6 0.63
Follow-up time (years) 453 9.7 ± 5.8 136 9.0 ± 5.1 0.10
Body mass index (kg/meter2) 453 27.5 ± 3.5 136 28.6 ± 3.9 <0.01
Smoking (pack-years) 444 21.0 ± 25.6 133 22.3 ± 25.3 0.35
Total cholesterol (mg/dL) 453 226.8 ± 35.6 136 234.2 ± 39.5 0.03
High-density lipoprotein (mg/dL) 453 49.2 ± 13.3 136 47.8 ± 11.1 0.21
Total cholesterol/HDL ratio 453 4.9 ± 1.4 136 5.1 ± 1.2 0.13
Categorical variables
Totalc N (%) Total N (%) P valueb
Smoking 453 136 0.19
  Never smokers 147 (32.5) 36 (26.5)
  Ever smokers 306 (67.5) 100 (73.5)
Education 433 131 0.60
  <high school 42 (9.7) 18 (13.7)
  high school 149 (34.4) 45 (34.4)
  some college 110 (25.4) 32 (24.4)
  ≥ 4 year college graduate 132 (30.5) 36 (27.5)
Hypertension 453 201 (44.4) 136 92 (47.8) 0.48
Diabetes 453 51 (11.3) 136 17 (12.5) 0.69

a P value from t-test or Wilcoxon rank-sum test (patella and tibia lead, total cholesterol, and total cholesterol to HDL ratio).

b P value from Chi-square test.

c Totals vary because of missing data.