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. 2016 Jul 8;311(2):H433–H444. doi: 10.1152/ajpheart.00176.2016

Table 1.

Effect of ARCN stimulation on Tcore

ARCN: NMDA Microinjections
Before, °C After, °C
DMN Microinjections
    aCSF 36.56 ± 0.5 36.94 ± 0.3
    Muscimol 36.65 ± 0.5 37.02 ± 0.3
    d-AP7+NBQX 36.58 ± 0.6 37.03 ± 0.3
    SHU9119 36.63 ± 0.5 37.06 ± 0.3
Before, °C After, °C
PVN Microinjections
    aCSF 37.34 ± 0.2 37.49 ± 0.1
    Muscimol 36.52 ± 0.4 36.95 ± 0.3
    d-AP7+NBQX 36.88 ± 0.5 37.27 ± 0.2
    SHU9119 37.43 ± 0.1 37.52 ± 0.1

Effects of ARCN stimulation on Tcore (°C). Microinjections of artificial cerebrospinal fluid (aCSF), muscimol, ionotropic glutamate receptors (iGLUR) antagonists, and melanocortin 3/4 receptor (MC3/4R) antagonist into the dorsomedial nucleus (DMN) or the paraventricular nucleus (PVN) did not significantly alter Tcore during stimulation of arcuate nucleus (ARCN) by N-methyl-d-aspartic acid (NMDA). AP7, D(-)-2-amino-7-phosphono-heptanoic acid; NBQX, 2,3-dioxo-6-nitro-1,2,3,4-tetrahydrobenzo-[f]quinoxaline-7-sulfonamide disodium; SHU9119, Ac-Nle-cyclo(-Asp-His-d-2-Nal-Arg-Trp-Lys)-NH2.

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