Table 1.
Effect of ARCN stimulation on Tcore
ARCN: NMDA Microinjections |
||
---|---|---|
Before, °C | After, °C | |
DMN Microinjections | ||
aCSF | 36.56 ± 0.5 | 36.94 ± 0.3 |
Muscimol | 36.65 ± 0.5 | 37.02 ± 0.3 |
d-AP7+NBQX | 36.58 ± 0.6 | 37.03 ± 0.3 |
SHU9119 | 36.63 ± 0.5 | 37.06 ± 0.3 |
Before, °C | After, °C | |
---|---|---|
PVN Microinjections | ||
aCSF | 37.34 ± 0.2 | 37.49 ± 0.1 |
Muscimol | 36.52 ± 0.4 | 36.95 ± 0.3 |
d-AP7+NBQX | 36.88 ± 0.5 | 37.27 ± 0.2 |
SHU9119 | 37.43 ± 0.1 | 37.52 ± 0.1 |
Effects of ARCN stimulation on Tcore (°C). Microinjections of artificial cerebrospinal fluid (aCSF), muscimol, ionotropic glutamate receptors (iGLUR) antagonists, and melanocortin 3/4 receptor (MC3/4R) antagonist into the dorsomedial nucleus (DMN) or the paraventricular nucleus (PVN) did not significantly alter Tcore during stimulation of arcuate nucleus (ARCN) by N-methyl-d-aspartic acid (NMDA). AP7, D(-)-2-amino-7-phosphono-heptanoic acid; NBQX, 2,3-dioxo-6-nitro-1,2,3,4-tetrahydrobenzo-[f]quinoxaline-7-sulfonamide disodium; SHU9119, Ac-Nle-cyclo(-Asp-His-d-2-Nal-Arg-Trp-Lys)-NH2.