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. 2016 Jul 1;311(2):H498–H507. doi: 10.1152/ajpheart.00998.2015

Fig. 2.

Fig. 2.

Exogenous chemerin-9 amplifies electrical field stimulation (EFS)-induced contraction through the chemerin receptor ChemR23. Isolated superior mesenteric arteries in the presence (+) and absence (−) of perivascular adipose tissue (PVAT) were exposed to vehicle or the ChemR23 antagonist CCX832 for 5 min prior to addition of vehicle or chemerin-9. A: representative traces of experimental results in the artery in the presence of PVAT. B and C: results for tissues with and without PVAT. Left: means ± SE; n, number of animals. *Significantly different from chemerin-9; °significantly different from vehicle, by 2-way ANOVA (P < 0.05). Right: chemerin-9-amplified contraction as a percentage of vehicle per frequency in the presence and absence of PVAT. †Significantly different from +PVAT value.