Table 4.
Compound | Concentration | Revertants per plate
|
MR |
---|---|---|---|
Bacteria strain TA100 | |||
QDs | 10 nM | 7/96 | 1.17 |
5 nM | 8/96 | 1.33 | |
2.5 nM | 4/96 | 0.67 | |
1.2 nM | 6/96 | 1 | |
0.6 nM | 0/96 | 0 | |
0.3 nM | 0/96 | 0 | |
QDs-Ind | 10 nM | 3/96 | 0.6 |
5 nM | 2/96 | 0.4 | |
2.5 nM | 2/96 | 0.4 | |
1.2 nM | 3/96 | 0.6 | |
0.6 nM | 0/96 | 0 | |
0.3 nM | 0/96 | 0 | |
Ind | 43 µM | 0/96 | 0 |
21.5 µM | 0/96 | 0 | |
10.7 µM | 0/96 | 0 | |
5.4 µM | 0/96 | 0 | |
2.7 µM | 0/96 | 0 | |
1.3 µM | 0/96 | 0 |
Notes: The concentration of Ind tested corresponds to the concentration of peptide present in each sample of QDs-Ind (range 10–0.3 nM).
Abbreviations: QDs, quantum dots; Ind, indolicidin; MR, mutagenicity ratio; QDS-Ind, quantum dots-indolicidin.