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Effect of renal medullary interstitial infusions of isosmotic (284 mosmol/kgH2O) or hyperosmotic saline (1,800 mosmol/kgH2O) on the relative inner medullary mRNA expression of endothelin-1 (ET-1) in anesthetized male rats. Values represent fold change from corresponding isosmotic saline levels. Data are means ± SE of 5–7 samples in each group. *P < 0.05 vs. corresponding isosmotic saline values.
