Table 4.
Excess mortality ratios from univariable and multivariable Poisson models assessing the risk of all, recurrence or progression, subsequent primary neoplasm, and non-neoplastic causes of death by treatment period
| Treatment period | All causes | Recurrence or progression | Subsequent primary neoplasms | Non-neoplastic causes | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Observed/expected | Univariable: EMR (95% CI) | Multivariable*: EMR (95% CI) | Observed/expected | Univariable: EMR (95% CI) | Multivariable*: EMR (95% CI) | Observed/expected | Univariable: EMR (95% CI) | Multivariable*: EMR (95% CI) | Observed/expected | Univariable: EMR (95% CI) | Multivariable*: EMR (95% CI) | ||||
| <1970 | 1329/228.1 | 1 (ref) | 1 (ref) | 638/0.0 | 1 (ref) | 1 (ref) | 295/79.7 | 1 (ref) | 1 (ref) | 396/148.5 | 1 (ref) | 1 (ref) | |||
| 1970-79 | 1247/125.0 | 0.9 (0.8 to 1.0) | 0.8 (0.7 to 0.8) | 708/0.0 | 1.0 (0.9 to 1.1) | 0.7 (0.6 to 0.7) | 240/26.9 | 0.9 (0.7 to 1.1) | 1.4 (1.1 to 1.7) | 299/98.1 | 0.7 (0.6 to 0.9) | 1.0 (0.8 to 1.3) | |||
| 1980-89 | 942/85.0 | 0.7 (0.6 to 0.7) | 0.5 (0.5 to 0.6) | 591/0.0 | 0.8 (0.7 to 0.9) | 0.4 (0.4 to 0.5) | 138/13.1 | 0.5 (0.4 to 0.6) | 0.9 (0.7 to 1.2) | 213/71.9 | 0.5 (0.4 to 0.6) | 0.9 (0.7 to 1.2) | |||
| 1990-2006 | 957/52.9 | 0.6 (0.6 to 0.7) | 0.3 (0.3 to 0.4) | 689/0.0 | 0.8 (0.7 to 0.9) | 0.3 (0.2 to 0.3) | 122/7.3 | 0.4 (0.3 to 0.5) | 0.9 (0.7 to 1.2) | 146/45.5 | 0.3 (0.2 to 0.4) | 0.6 (0.4 to 0.8) | |||
| P for trend† | <0.01 | <0.01 | <0.01 | <0.01 | <0.01 | 0.10 | <0.01 | <0.01 | |||||||
EMR=excess mortality ratios.
*Adjusted for sex, first primary neoplasm diagnosis, age at diagnosis, and attained age.
†Calculated using likelihood ratio tests to assess the effect of treatment period.