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. 2016 Sep 1;354:i4351. doi: 10.1136/bmj.i4351

Table 8.

Excess mortality ratios from univariable and multivariable Poisson models assessing the risk of circulatory, respiratory, and external causes of death by treatment period

Treatment period Circulatory causes Respiratory causes External causes*
Observed/expected Univariable: EMR (95% CI) Multivariable†: EMR (95% CI) Observed/expected Univariable: EMR (95% CI) Multivariable†: EMR 95% CI) Observed/expected Univariable: EMR (95% CI) Multivariable†: EMR (95% CI)
<1970 145/50.0 1 (ref) 1 (ref) 61/14.3 1 (ref) 1 (ref) 65/40.9 1 (ref) 1 (ref)
1970-79 74/16.7 0.5 (0.3 to 0.8) 0.9 (0.6 to 1.4) 48/5.2 0.8 (0.5 to 1.3) 1.0 (0.7 to 1.7) 55/45.2 0.4 (0.1 to 1.8) 0.7 (0.3 to 1.7)
1980-89 63/7.8 0.5 (0.3 to 0.7) 1.3 (0.8 to 2.0) 36/2.9 0.6 (0.4 to 1.0) 0.9 (0.5 to 1.6) 41/38.9 0.1 (0.0 to 33.7) 0.5 (0.2 to 1.5)
1990-2006 18/3.5 0.1 (0.1 to 0.2) 0.4 (0.2 to 0.6) 19/1.8 0.3 (0.2 to 0.5) 0.4 (0.2 to 0.8) 27/26.7 0.0 (0.0 to 0.0) 0.0 (0.0 to 0.0)
P for trend‡ <0.01 0.19 <0.01 0.01 <0.01 <0.01

EMR=excess mortality ratios.

*Includes deaths due to transportation accidents, falls, drowning, fire, suicide, etc.

†Adjusted for sex, first primary neoplasm type, age at diagnosis, and attained age.

‡Calculated using likelihood ratio tests to assess the effect of treatment period.