TABLE 1.
C. albicans strains used in this study
| Strain | Description or name | Genotype | Source or reference |
|---|---|---|---|
| ATCC 44858 | Isolate from parrot | Originally from Janssen Pharmaceutica | |
| NCPF 3153 | Clinical isolate | Reference antigen strain, Public Health Mycology Reference Laboratory | |
| RV4688 | Clinical isolate | Originally from Janssen Pharmaceutica | |
| AM2003-020 | Isolate from healthy carrier | ||
| 73/034 | Isolate from healthy carrier | ||
| SC5314 | Clinical isolate | 28 | |
| CAF2-1 | ura3Δ-iro1Δ::imm434/URA3 | 28 | |
| CAI-4 | ura3Δ-iro1Δ::imm434/ura3Δ-iro1Δ::imm434 | 28 | |
| NGY152 | CAI-4/CIp10 | ura3Δ-iro1Δ::imm434/Δura3Δ-iro1Δ::imm434/Clp10 | 60 |
| NGY23 | mnt1Δ/mnt1 | As CAI-4 but mnt1Δ::hisG/mnt1Δ::hisG-URA3-hisG | 15 |
| NGY158 | mnt1Δ/Clp10 | As CAI-4 but mnt1Δ::hisG/mnt1Δ::hisG/Clp10 | Bates et al., unpublished |
| NGY148 | mnt1Δ/Clp10-MNT1 | As CAI-4 but mnt1Δ::hisG/mnt1Δ::hisG/Clp10-MNT1 | Bates et al., unpublished |
| NGY337a | mnt1Δ/mnt2Δ/Clp10 | As CAI-4 but mnt1-IPF6318-mnt2Δ::hisG/mnt1-IPF6318- mnt2Δ::hisG/Clp10 | Bates et al., unpublished |
| NGY105 | mnt2Δ | As CAI-4 but mnt2Δ::hisG/mnt2Δ::hisG-URA3-hisG | Bates et al., unpublished |
| NGY145 | mnt2Δ/Clp10 | As CAI-4 but mnt2Δ::hisG/mnt2Δ::hisG/Clp10 | Bates et al., unpublished |
| NGY103 | MNT2/mnt2Δ | MNT2/mnt2Δ::hisG-URA3-hisG | Bates et al., unpublished |
| NGY336 | MNT2/mnt2Δ/Clp10 | MNT2/mnt2Δ::hisG/Clp10 | Bates et al., unpublished |
| NGY63 | mnt3Δ | As CAI-4 but mnt3Δ::hisG/mnt3Δ::hisG-URA3-hisG | Thomson et al., unpublished |
| NGY146 | mnt3Δ/Clp10 | As CAI-4 but mnt3Δ::hisG/mnt3Δ::hisG/Clp10 | Thomson et al., unpublished |
| NGY71 | mnt4Δ | As CAI-4 but mnt4Δ::hisG/mnt4Δ::hisG-URA3-hisG | Bates et al., unpublished |
| NGY313 | mnt4Δ/Clp10 | As CAI-4 but mnt4Δ::hisG/mnt4Δ::hisG/Clp10 | Bates et al., unpublished |
| NGY71 | mnt5Δ | As CAI-4 but mnt5Δ::hisG/mnt5Δ::hisG-URA3-hisG | Thomson et al., unpublished |
| NGY147 | mnt5Δ/Clp10 | As CAI-4 but mnt5Δ::hisG/mnt5Δ::hisG/Clp10 | Thomson et al., unpublished |
| NGY151 | mnt5Δ/Clp10-MNT5 | As CAI-4 but mnt5Δ::hisG/mnt5Δ::hisG/Clp10-MNT5 | Thomson et al., unpublished |
| DH5 | mnn4Δ | As CAI-4 but mnn4Δ::hisG/mnn4Δ::hisG-URA3-hisG | Hobson et al., unpublished |
| DH15 | mnn4Δ/Clp10 | As CAI-4 but mnn4Δ::hisG/mnn4Δ::hisG/Clp10 | Hobson et al., unpublished |
| DH11 | mnn4Δ/Clp10-MNN4 | As CAI-4 but mnn4Δ::hisG/mnn4Δ::hisG/Clp10-MNN4 | Hobson et al., unpublished |
| DH13 | mnn4Δ/Clp10-MNN4nb | As CAI-4 but mnn4Δ::hisG/mnn4Δ::hisG/Clp10-MNN4n | Hobson et al., unpublished |
| DH17 | MNN4/mnn4Δ | MNN4/mnn4Δ::hisG/Clp10 | Hobson et al., unpublished |
| GTC43 | gcn4Δ | As CAI-4 but gcn4Δ::hisG/gcn4Δ::hisG-URA3-hisG | 84 |
| GTC41 | GCN4/gcn4Δ | As CAI-4 but GCN4/gcn4Δ::hisG-URA3-hisG | Tournu et al., unpublished |
| GTC45 | gcn4Δ/Clp10 | As CAI-4 but gcn4Δ::hisG/gcn4Δ::hisG/Clp10 | Tournu et al., unpublished |
| GTC49a | gcn4Δ/Clp10-GCN4(a) | As CAI-4 but gcn4Δ::hisG/gcn4Δ::hisG/Clp10-ACT1p-GCN4 | Tournu et al., unpublished |
| GTC49b | gcn4Δ/Clp10-GCN4(b) | As CAI-4 but gcn4Δ::hisG/gcn4Δ::hisG/Clp10-ACT1p-/GCN4 | Tournu et al., unpublished |
| GTC47 | gcn4Δ/pMET-GCN4 | As CAI-4 but gcn4Δ::hisG/gcn4Δ::hisG/pMET-GCN4 | Tournu et al., unpublished |
| MMC3 | nrg1Δ | As CAI-4 but nrg1Δ::hisG/nrg1Δ::hisG-URA3-hisG | 60 |
| NGY205 | och1Δ | och1Δ::hisG/och1Δ::hisG | Thomas et al., unpublished |
| BH1-1-1 | sap3Δ | As CAI-4 but sap3Δ::hisG/sap3Δ::hisG-URA3-hisG | 35 |
| VC3.9 | sap3Δ/Clp10 | As CAI-4 but sap3Δ::hisG/sap3Δ::hisG/Clp10 | Copping et al., unpublished |
| rad52 heterozygote | RAD52/rad52Δ | As CAI-4 but RAD52/rad52Δ::hisG-URA3-hisG | Ciudad et al., unpublished |
| rad52 reintegrant | rad52Δ/RAD52 | As CAI-4 but rad52Δ::hisG/RAD52::URA3-hisG | Ciudad et al., unpublished |
a
Deletion spans MNT1, MNT2, and intervening ORF IPF6318 (putative β-glucosidase).
b
Multicopy reintegrant.