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. 2016 Sep 1;11(9):e0162090. doi: 10.1371/journal.pone.0162090

Table 3. Factors associated with abnormal CXR and TB disease among the household contacts who had their CXR done (N = 544) in Chennai, India.

Characteristic Total N CXR Abnormal n (%) Unadjusted OR (95% CI, p value) Adjusted OR (95% CI, p value) TB disease n (%) Unadjusted OR (95% CI, p value) Adjusted O.R. (95% CI, p value)
Age in years
0–14 194 10 5 1.0 (Ref) 1.0 (Ref) 3 2 1.0 (Ref) 1.0 (Ref)
15–44 273 38 14 3.0(1.4–6.1, 0.003) 2.3(0.9–6.0, 0.09) 23 8 5.9 (1.7–19.8, 0.004) 7.3(1.4–36.7, 0.02)
>44 77 23 30 7.8(3.5–17.5, <0.001) 5.5(1.6–19.0, 0.01) 3 4 2.6(0.5–13.1, 0.25) 2.2(0.2–21.4, 0.5)
Sex
Male 220 38 17 1.8(1.1–3.0, 0.02) 2.2(1.2–3.9, 0.01) 17 8 2.2(1.1–4.6, 0.04) 2.0(0.8–4.9, 0.14)
Female 324 33 10 1.0 (Ref) 1.0 (Ref) 12 4 1.0 (Ref) 1.0 (Ref)
Relationship to the index case*
Spouse 155 17 11 2.3 (1.1–4.9, 0.04) 1.4 (0.5–3.9. 0.47) 5 3 1.5(0.4–5.4, 0.5) 0.7(0.2–3.0, 0.67)
Parent 64 18 28 7.3 (3.3–16.1, <0.001) 2.7 (0.8–9.2, 0.12) 4 6 3.1(0.8–11.8, 0.1) 3.2(0.5–19.9, 0.21)
Child 235 12 5 1.0 (Ref) 1.0 (Ref) 5 2 1.0 (Ref) 1.0 (Ref)
Sibling 47 11 23 5.7(2.3–13.8, 0.001) 3.4 (1.2–9.7, 0.02) 6 13 6.7(2.0–23.1, 0.002) 2.6(0.7–10.0, 0.16)
Others** 37 8 22 5.1(1.9–13.6, 0.001) 3.7 (1.3–10.8, 0.02) 4 11 5.6(1.4–21.8, 0.01) 4.1(1.0–17.2, 0.06)

* Details missing in 6 contacts

**Included other second degree relatives (Grandchild, cousin, uncle).