Table 1. GBS MV associated proteins and their predicted biological function.
Band No. a | Locus | Protein ID | Product | Mol. wt. (kDa) | Mascot Score | No. of peptides matched | Seq. coverage (%) | Location b | Biological role |
---|---|---|---|---|---|---|---|---|---|
1 | SAK_0186 | YP_328859.1 | IgA binding beta antigen | 131 | 215 | 39 | 36 | Cell wall | Phagocytosis escape |
2 | SAK_1284 | YP_329897.1 | Hyaluronate lyase | 122 | 208 | 37 | 37 | Cell membrane | ECM degradation |
3 | SAK_1293 | YP_329906.1 | Neutral metallo protease fused to ChW-repeats | 94 | 199 | 30 | 40 | Cell membrane | ECM degradation |
4 | SAK_1695 | YP_330297.1 | Immunogenic secreted protein | 55 | 122 | 17 | 48 | Extracellular | Predicted hydrolase activity |
5 | SAK_0206 | YP_328879.1 | Oligopeptide ABC transporter oligopeptide binding protein | 60 | 136 | 19 | 43 | Extracellular | Transporter |
6 | SAK_0887 | YP_329509.1 | Elongation factor Tu | 44 | 222 | 25 | 63 | Cytoplasm | Translation elongation |
7 | SAK_0050 | YP_328743.1 | PcsB protein | 45 | 93 | 9 | 43 | Cell membrane | Cell division |
8 | SAK_1983 | YP_330575.1 | cAMP factor | 28 | 76 | 10 | 40 | Cell membrane | Pore forming toxin |
aSee Fig 2B.
bSubcellular locations were predicted by LocateP database and confirmed by pSORT and TMHMM algorithms.