Table 2. List of DORN1 interacting residues with ATP obtained from prediction and target docking.
| Loop | Knowledge based predictions1 | Target docking2 |
|---|---|---|
| A | Gly98, His99 | Glu96 (1H), Gly98, His99 (2H) |
| B | Thr117, Arg118 | Thr117 (2H), Arg118 (2H) |
| C | Ile143, Asn145 | Ile143, Trp144 (1H), Pro146 |
| D | Gly245, Thr246, Ala247 | Gly245, Thr246 (3H), Ala247 (1H) |
| Total residues | 9 | 11 |
1 Consensus residues were predicted by using different online prediction tools, numbers next to residue names represent actual positions in the full length sequence of DORN1.
2 Residues follow by a number and a letter H within round-brackets denote number of hydrogen bonds sharing with ATP, other residues without a number and a letter are those only interact with ATP through hydrophobic interaction.