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. 2016 Sep 6;188(12):E281–E288. doi: 10.1503/cmaj.151528

Table 4:

Adjusted odds of cervical abnormalities (worst cytology result),* by vaccination status

Dose Abnormal Low grade High grade** High grade**††




Crude OR (95% CI) Adjusted OR§ (95% CI) Crude OR (95% CI) Adjusted OR§ (95% CI) Crude OR (95% CI) Adjusted OR§ (95% CI) Crude OR (95% CI) Adjusted OR§ (95% CI)
0 1 1 1 1 1 1 1 1

1 0.88 (0.64–1.20) 0.86 (0.62–1.18) 0.91 (0.66–1.26) 0.9 (0.64–1.24) 0.48 (0.12–1.95) 0.45 (0.11–1.83) 0.48 (0.12–1.97) 0.45 (0.11–1.87)

2 1.07 (0.83–1.36) 1.08 (0.84–1.38) 1.14 (0.89–1.46) 1.15 (0.90–1.49) 0.16 (0.02–1.18) 0.17 (0.02–1.20) 0.16 (0.02–1.16) 0.16 (0.02–1.17)

≥ 1 0.75 (0.67–0.84) 0.78 (0.69–0.87) 0.78 (0.69–0.87) 0.81 (0.71–0.92) 0.42 (0.27–0.67) 0.45 (0.27–0.73) 0.44 (0.28–0.69) 0.46 (0.28–0.75)

≥ 3 0.70 (0.62–0.79) 0.72 (0.63–0.82) 0.72 (0.62–0.82) 0.74 (0.64–0.85) 0.45 (0.28–0.73) 0.48 (0.28–0.81) 0.47 (0.29–0.76) 0.50 (0.30–0.85)

Note: ASC-H = atypical squamous cells, cannot rule out a high-grade lesion, ASC-US = atypical squamous cells of undetermined significance, CI = confidence interval, HSIL = high-grade squamous intraepithelial lesion, LSIL = low-grade squamous intraepithelial lesion, OR = odds ratio.

*

Cytology with worst result between Jan. 1, 2012, and Aug. 14, 2015.

Control: negative cytology result.

Abnormal: ASC-US, LSIL, ASC-H or HSIL.

§

Adjusted for age, income, rural/urban residency and laboratory site.

Low grade: ASC-US or LSIL.

**

High grade: ASC-H or HSIL.

††

Control: negative and low-grade (ASC-US, LSIL) results.