Table 1. Characteristics of 150 CAP participants used in RNA-seq analysis.

	AA men	AA women	Cau men	Cau women	All
N	26	24	60	40	150
Ethnicity	Afr. Am	Afr. Am	Caucasian	Caucasian	66.7% Cau
Gender	Male	Female	Male	Female	57.3% male
% smokers	15.4%	12.5%	10.0%	7.5%	10.7%
Age (years)	50.6±12.6	52.6±13.2	53±12.2	55.9±12.5	53.3±12.5
BMIa	29.4±5.5	30.9±5.8	27.7±4.2	27.5±6.5	28.5±5.5
Baseline TG	132±65.2	99±42.6	131.5±65.8	122.1±64.1	123.9±62.6
Statin TG	110.9±55.9	78.5±33.4	104.6±70.8	92.8±49.3	98.4±58.6
% Change TG	−9.3±41.4%	−15.7±26.5%	−20.2±25.6%	−21.8±18.4%	−18.0±27.6%
Baseline TC	206.4±40.5	202.0±34.6	207.0±33.4	221.1±38.0	209.9±36.4
Statin TC	149.7±35.5	152.9±27.6	146.7±27.8	156.2±33.4	150.8±30.7
% Change TC	−26.9±13.3%	−23.9±10.4%	−28.9±9.9%	−28.9±11.5%	−27.8±11.1%
Baseline LDL-C	134.4±36.9	121±35.7	134.3±31.6	135.5±33.9	132.5±33.9
Statin LDL-C	80.6±28.3	70.9±23.3	77.6±23.9	74.7±27.9	76.3±25.6
% Change LDL-C	−39.4±15.2%	−40.7±13.1%	−42.2±13.1%	−44.7±14.9%	−42.2±13.9%
Baseline HDL-Cb	45.6±10.9	61.4±20.5	46.6±12.1	61.4±20.6	52.7±17.6
Statin HDL-Cb	47.1±10.6	66.5±22.7	48.4±13.0	63.2±20.2	55.0±18.4
% Change HDL-C	4.3±11.0%	8.7±10.8%	4.5±11.4%	3.6±9.4%	4.9±10.8%

Abbreviations: AA, African American; BMI, body mass index; CAP, Cholesterol and Pharmacogenetics; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglyceride. Values are mean±s.d. Baseline and statin lipid measurements are in mg dl⁻¹.

^aBMI was significantly different between the 100 Caucasians and 50 African Americans (P=0.007, Wilcoxon rank-sum test).

^bBaseline and on-statin HDL-cholesterol levels were significantly different between the 86 men and 64 women (P=3 × 10⁻⁸ for both, Wilcoxon rank-sum test). None of the other phenotypes or covariates listed here were significantly different (P<0.05) between races and sexes in this N=150 CAP subset.