Table 2.
Genes expressed 2-fold or greater in G+/I− versus I+/G− NK cells.
| Gene | Protein | Function | Fold-change | p value |
|---|---|---|---|---|
| Ikzf2 | IKAROS Family Zinc Finger 2 (Helios) | Transcription factor | 2.10 | 2.17E-06 |
| Csf2 | GM-CSF | granulocyte/macrophage production/differentiation |
2.17 | 1.31E-05 |
| Clip3 | CAP-GLY Domain Containing Linker Protein 3 | links microtubules with cellular organelles. | 2.01 | 1.31E-04 |
| Klra1 | Ly49a | Class I MHC receptor | 2.47 | 7.40E-07 |
| Dll1 | Delta-Like 1 | Notch ligand | 2.31 | 9.82E-05 |
| Sox6 | SRY-box 6 | Transcription factor | 2.21 | 1.83E-05 |
| Chl1 | Cell Adhesion Molecule Homologous to L1CAM | Cell Adhesion | 2.59 | 2.41E-05 |
| Gpr55 | G Protein-Coupled Receptor 55 | Receptor for L-alpha-lysophosphatidylinositol | 2.64 | 1.71E-05 |
| Slamf6 | SLAM Family Member 6 | Coreceptor for NK cell activation | 2.85 | 3.38E-06 |
| Cd3g | CD3-gamma | TCR signaling | 3.24 | 4.83E-06 |
| Il7r | IL-7 Receptor Subunit Alpha | lymphocyte survival | 3.96 | 8.11E-08 |
| Cd3d | CD3-delta | TCR signaling | 2.54 | 3.40E-05 |
| Dpysl5 | Dihydropyrimidinase-Like 5 | Neuron differentiation, interacts with L1CAM | 3.21 | 1.03E-05 |
| Cd3e | CD3-epsilon | TCR signaling | 13.77 | 5.87E-07 |
| Klra7 | Ly49g | Class I MHC receptor | 86.89 | 5.91E-14 |