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. Author manuscript; available in PMC: 2017 Sep 5.
Published in final edited form as: Angew Chem Int Ed Engl. 2016 Jul 12;55(37):11193–11197. doi: 10.1002/anie.201603746

Table 3.

Potencies of compounds 24–32 on hNAAA.graphic file with name nihms-805426-t0004.jpg

Compound Y hNAAA IC50 (μM)[a]
24 H 0.43 ± 0.03
25 6-Cl 1.55 ± 0.29
26 6-CF3 7.2
27 6-CH3 6.87
28 6-OCH3 5.73
29 4-F 0.55 ± 0.20
30 5-F 2.95 ± 0.84
31 7-F 0.30 ± 0.02
32 7-Cl 0.71 ± 0.21
[a]

See Footnote for Table 1.