Table 3. Sensitivity and specificity of S100B and S100B autoantibodies to detect brain metastasis.

Test	Sensitivity (%)	Specificity (%)
S100B (ng/mL)
0.023	100	6
0.058	89	43
0.070	55	59
0.100	33	80
0.155	11	95
Anti-S100B IgG (AU)
1.0	94.4	2.8
1.5	66.7	33.6
2.0	5.6	84.1
2.5	0	98.9
S100B >0.058 ng/mL + anti-S100B IgG (AU)
<1.0	5.6	97.3
<1.5	33.3	83.6
<2.0	89	58.2
<2.5	89	45.5

IgG, immunoglobulin G.