Table S1. SVD grade and S100B and anti-S100B IgG levels (n=109). The results were analyzed with one-way ANOVA.

SVD grade	S100B (ng/mL)	Anti-S100B IgG (AU)
White matter lesions
0 (n=38)	0.065	1.47
1 (n=58)	0.073	1.69
2 (n=13)	0.067	1.58
3	–	–
P value	0.58	0.07
Basal ganglia lesions
0 (n=102)	0.069	1.60
1 (n=6)	0.096	1.34
2 (n=1)	0.131	1.81
3	–	–
P value	0.13	0.35
Sum score from white matter + basal ganglia lesions
0 (n=38)	0.065	1.47
1 (n=56)	0.072	1.68
2 (n=13)	0.065	1.65
3 (n=2)	0.11	1.57
P value	0.28	0.25

SVD, small vessel disease; IgG, immunoglobulin G.