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Strand-strand contact maps from tethered two-chain W42R simulations involving the 2–3 disulfide. A, the most commonly interacting β-strands are strand 1 and the two strands most involved in the domain interface (highlighted in yellow). The N-terminal domain is blue; the C-terminal domain is red. B, combined contact maps for all simulations showing frequency of pairwise non-native strand-strand interactions.
