Table 1.
Double-blind randomized studies based on tilt test findings.
| Trial | Inclusion criteria | Inactive pacemaker group | Active pacemaker group | Analysis | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| N | Female (%) | Mean age (years) | Recurrence of syncope | N | Female (%) | Mean age | Recurrence of syncope | |||
| VPS II | ≥ 6 syncopal episodes or ≥ 3 episodes in 2 years and HR x BP < 6000 bpm x mmHg | 52 | 48.1 | 47.8 | 42% | 48 | 72.9 | 50.8 | 33% | Relative risk reduction 30%, p=0.14 |
| SYNPACE | ≥ 6 syncopal episodes in all life and with asystole or mixed response | 13 | 54 | 54 | 38% | 16 | 69 | 52 | 50% | p=0.58 |
N: number of patients.