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. 2016 Sep 2;6:32565. doi: 10.1038/srep32565

Table 2. Generation of Tyr mutant founder mice by SaCas9 and SpCas9.

Cas9 gRNA Pups/Transferred (%) Albino pups (%) Coat color Mosaic pups (%) Mutant black pups/Black pups Mutant pups (%)
SaCas9 G1 11/75 (14.7%) 8 (72.7%) 0 (0%) 1/3 9 (81.8%)
G2 21/158 (13.3%) 8 (38.1%) 3 (14.3%) 2/10 13 (61.9%)
SpCas9 G3 12/99 (12.1%) 8 (66.7%) 0 (0%) 0/4 8 (66.7%)
G4 16/123 (13.0%) 11 (68.8%) 2 (12.5%) 0/3 13 (81.3%)