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. 2016 Sep 2;6:32739. doi: 10.1038/srep32739

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Copyright © 2016, The Author(s)

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(A) The interactions between DDX3X and Drosha complex tested by immunoprecipitation (IP) experiment. The uncropped full-length blots were presented in Figure S3. (B) The interactions between DDX3X and Dicer tested by immunoprecipitation (IP) experiment. The uncropped full-length blots were presented in Figure S3. (C) Relative pri-miRNA expression levels of DDX3X-dependent miRNAs (miR-1, miR-141, miR-145, miR-19b, miR-20a and miR-34a) in DDX3X KD cell lines compared with negative control (NC) cell lines. The DDX3X-independent miRNA (miR-21) was used as an internal control. The asterisk(s) (*^,**) indicate a significant difference (p < 0.05, p < 0.01) respectively. (D) Relative mature miRNA expression levels of DDX3X-dependent miRNAs in DDX3X KD cell lines compared with NC cell lines. The DDX3X-independent miRNA (miR-21) was used as an internal control. The asterisks (**) indicate a significant difference (p < 0.01). (E) Relative pri-miRNA expression levels of DDX3X-dependent miRNAs in DDX3X OE cell lines compared with NC cell lines. The DDX3X-independent miRNA (miR-21) was used as an internal control. The asterisk(s) (*^,**) indicate a significant difference (p < 0.05, p < 0.01) respectively. (F) Relative mature miRNA expression levels of DDX3X-dependent miRNAs in DDX3X OE cell lines compared with NC cell lines. The DDX3X-independent miRNA (miR-21) was used as an internal control. The asterisk(s) (*^,**) indicate a significant difference (p < 0.05, p < 0.01) respectively.