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. Author manuscript; available in PMC: 2017 May 13.
Published in final edited form as: Circ Res. 2016 May 13;118(10):1593–1611. doi: 10.1161/CIRCRESAHA.116.307505

Figure 4.

Figure 4

Ultrastructure of young and aged Fischer 344 rat hearts. (a) Electron micrograph of myocardium of a 6-month rat. (b) Myocardium of a 28-month rat. SSM are clustered in groups under the sarcolemmal membrane; IFM are between the myofibrils. There are no structural differences noted between the two ages.24 (c) Isolated SSM from a 24-month rat, osmium-extracted. The cristae morphology is mixed between lamelliform and tubular. (d) Isolated IFM from a 24-month rat, osmium-extracted. Cristae are primarily tubular.47 Magnification in (a) and (b) is 6000 and the bar in (c) and (d) is 1 μm.