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. 2016 Aug 15;8(8):3351–3363.

Figure 2.

Figure 2

The protective effect of metformin on the permeability of bEnd3 cell monolayers. A. bEnd3 cell monolayers were exposed to 1% O2 hypoxic condition for six hours while incubated with metformin. B. bEnd3 cell monolayers were exposed to a recombinant vascular endothelial growth factor (VEGF; 50 ng/ml) while incubated with metformin for 12 h. *p<0.01 compared with the control group. #p<0.01 compared with 0 mM metformin group.