TABLE 2.
Chemical Specific Model Parameters Estimated Using GastroPlus
Chemical | PFOS | Triclosan | Pyridaben | Fluazinam |
---|---|---|---|---|
Fraction unbound | 0.092 | 0.072 | 0.067 | 0.092 |
Lung PC | 0.21 | 0.95 | 0.95 | 0.95 |
Brain PC | 0.05 | 11.10 | 11.13 | 11.17 |
Fat PC | 0.05 | 25.73 | 26.36 | 24.7 |
Liver PC | 0.09 | 6.94 | 6.96 | 7 |
Skin PC | 0.28 | 5.26 | 5.28 | 4.14 |
Kidney PC | 0.13 | 4.21 | 4.22 | 4.24 |
Mammary PC | 0.05 | 4.26 | 4.27 | 4.28 |
Uterus/Placenta PC | 0.14 | 4.22 | 4.23 | 4.24 |
Slowly Perfused PC | 0.12 | 5.26 | 5.28 | 5.3 |
Rapidly Perfused PC | 0.2 | 4.26 | 4.27 | 4.28 |