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Top: EcMetAP1 with no inhibitors (Co(II) cofactors) (PDB: 2MAT). Bottom: Compound (10) bound to the active site of EcMetAP1 (PDB: 1YVM). The color scheme is as follows for both images: blue spheres = nickel metals; light green compound = thiabendazole; yellow dashes represent coordination to the metals from residues or the inhibitors.
