Table 10.
The role of basophil activation test in the diagnosis of immediate type drug hypersensitivity to betalactam antibiotics
| Penicillin 20 % (n = 13) |
Aminopenicillins 38 % (n = 24) |
Cephalosporins 42 % (n = 27) |
Total 100 %(n = 64) |
|
|---|---|---|---|---|
| positive in vivo results and negative BAT | 23 % (n = 3) | 17 % (n = 4) | – | 11 % (n = 7) |
| negative in vivo results as well as absence of specific IgE and positive BAT | 15 % (n = 2) | 17 % (n = 4) | 22 % (n = 6) | 19 % (n = 12) |
| positive in vivo results and positive BAT | – | 8 % (n = 2) | 4 % (n = 1) | 4.5 % (n = 3) |
| positive in vivo results, positive specific IgE and negative BAT | – | 4 % (n = 1) | – | 1.5 % (n = 1) |
| negative in vivo results and negative BAT | 62 % (n = 8) | 54 % (n = 13) | 74 % (n = 20) | 64 % (n = 41) |