Table 2.
Clinical characteristics of LTG-induced cADRs group and LTG-tolerant group
| LTG-induced cADRs group (n = 16) | LTG-tolerant group (n = 50) | p value | |
|---|---|---|---|
| Gender (male: female) | 6:10 | 12:38 | 0.340 |
| 1:2 (SJS/TEN) | 1.000 | ||
| 5:8 (MPE) | 0.353 | ||
| Mean age (years) | 35.5 ± 21.7 | 38.2 ± 19.0 | 0.646 |
| 52.3 ± 24.0 (SJS/TEN) | 0.415 | ||
| 32.0 ± 20.9 (MPE) | 0.353 | ||
| Starting dosage of LTG (mg/day) | 51.6 ± 26.6 | 77.6 ± 62.0 | 0.109 |
| 41.7 ± 14.4 (SJS/TEN) | 0.325 | ||
| 53.8 ± 28.6 (MPE) | 0.186 |
No significant differences were observed in gender, mean age, and mean starting dosage of LTG between cases and LTG-tolerant controls