Table 1.
FVC | n | Onset age (years) | Gender, n (male:female) | Duration (months) | Bulbar onset | Upper limb onset | Lower limb onset | ALSFRS-R score | Fib-psw in the FID | Fib-psw in the TA | Fib-psw in the RA |
---|---|---|---|---|---|---|---|---|---|---|---|
≥80% | 79 | 50.5 ± 10.9 | 49:30 | 15.1 ± 10.2 | 14 | 41 | 24 | 41.6 ± 4.6 | 68 | 71 | 60 |
<80% | 49 | 53.3 ± 10.6 | 30:19 | 19.0 ± 15.6 | 3 | 32 | 14 | 37.5 ± 6.7* | 45 | 46 | 47* |
t | – | 1.438 | – | 1.538 | – | – | – | 3.773 | – | – | – |
χ2 | – | – | 0.008 | – | 3.533 | 2.218 | 0.047 | – | 0.970 | 0.213 | 8.793 |
P | – | 0.153 | 0.928 | 0.128 | 0.060 | 0.136 | 0.828 | <0.001 | 0.325 | 0.645 | 0.003 |
*P value for contrast of variates between patients with FVC ≥80% or not; P<0.05, as compared with patients with FVC ≥80%. Values are presented as n or mean ± SD. Fib-psw: Fibrillations and positive sharp waves; RA: Rectus abdominis; ALS: Amyotrophic lateral sclerosis; FVC: Forced vital capacity; ALSFRS-R: Revised ALS Functional Rating Scale; FID: First interosseus dorsalis; TA: Tibialis anterior; –: Not applicable; SD: Standard deviation.