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The mean fold changes are shown for miRNA species that were significantly elevated and in common during peak injury phases in chemically treated animals with respect to controls. Early injury is denoted as the first time point in each study with histologic evidence of cellular injury (6 h for ANIT, 1 d for FP004BA). Peak injury is designated as the time points with the highest magnitude of elevation of ALT, AST, T bili, and ALP (48 h for ANIT, 3 d for FP400BA).
