TABLE 3.
Hepatic MiRNA Alterations 24 and 120 h Following a Single Oral ANIT Administration (50 mg/kg)
| MiRNA | 24 h | 120 h |
|---|---|---|
| miR-130 a‐3p | 1.41 | 1.28 |
| miR-132‐3p | 1.46 | 2.67 |
| miR-146 b-5p | 2.04 | 1.92 |
| miR-16‐5p | 1.13 | 1.30 |
| miR-182‐5p | 2.33 | 3.04 |
| miR-191‐5p | 1.01 | 1.56 |
| miR-199 a‐3p | −1.01 | 1.98 |
| miR-200 c‐3p | 1.29 | 1.60 |
| miR-214‐3p | 1.14 | 1.77 |
| miR-218‐5p | 1.15 | 1.71 |
| miR-21 a‐5p | 1.41 | 1.97 |
| miR-223‐3p | 1.53 | 1.62 |
| miR-24‐2‐5p | 1.26 | 1.55 |
| miR-27 a‐3p | 1.22 | 1.32 |
| miR-301 b‐3p | 1.43 | 1.40 |
| miR-34 a‐5p | 1.33 | 1.74 |
| miR-429‐3p | 1.04 | 2.24 |
| miR-743 a‐3p | 1.55 | 3.16 |
| miR-872‐3p | 1.20 | 1.36 |
| miR-872‐5p | 1.27 | 1.38 |
| miR-881‐5p | −1.75 | −1.58 |
The fold changes of 22 miRNAs significantly altered by treatment, independent of time, in liver 24 and 120 h following a single dose of ANIT (50 mg/kg) are shown. Contrast was interrogated to determine significant miRNA alterations occurring at each time point. Bold text indicates a miRNA was significantly altered, at a given time point (P > .05). Italics text indicates that the miRNA fold change was not significant at a given time point.