Table 2.
Frequency of raltegravir adoption over time, by patient characteristic
| Characteristic | Number of raltegravir adoptors at each time point |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 180 Days |
360 Days |
720 Days |
|||||||
| N (%) | χ2 (df)* | P | N (%) | χ2 (df)* | P | N (%) | χ2 (df)* | P | |
| Overall | 197 (16.1) | 318 (26.0) | 433 (35.4) | ||||||
| Residence | |||||||||
| Urban | 171 (17.3) | 5.24 (1) | 0.02 | 272 (27.5) | 5.90 (1) | 0.02 | 359 (36.3) | 1.70 (1) | 0.19 |
| Rural | 26 (11.2) | 46 (19.7) | 74 (31.8) | ||||||
| Age | |||||||||
| 0–40 | 10 (8.4) | 11.0 (3) | 0.01 | 23 (19.3) | 4.93 (3) | 0.18 | 34 (28.6) | 6.12 (3) | 0.11 |
| 41–50 | 84 (19.4) | 115 (26.6) | 156 (36.0) | ||||||
| 51–60 | 73 (14.3) | 131 (25.6) | 176 (34.4) | ||||||
| 61 plus | 30 (19.0) | 49 (31.0) | 67 (42.4) | ||||||
| Gender | |||||||||
| Male | 196 (16.5) | 4.10 (1) | 0.04 | 314 (26.4) | 3.12 (1) | 0.08 | 425 (35.7) | 1.56 (1) | 0.21 |
| Female | 1 (3.1) | 4 (12.5) | 8 (25.0) | ||||||
| Race/ethnicity | |||||||||
| Black | 98 (14.6) | 3.33 (3) | 0.34 | 166 (24.7) | 2.31 (3) | 0.51 | 230 (34.2) | 2.19 (3) | 0.53 |
| White, non-hispanic | 77 (17.6) | 123 (28.2) | 165 (37.8) | ||||||
| Other | 16 (18.2) | 21 (23.9) | 28 (31.8) | ||||||
| Missing | 6 (24.0) | 8 (32.0) | 10 (40.0) | ||||||
| CD4 count | |||||||||
| 0–50 | 90 (17.8) | 10.5 (5) | 0.06 | 149 (29.4) | 19.8 (5) | 0.001 | 200 (39.5) | 24.6 (5) | <0.001 |
| 51–200 | 39 (18.8) | 66 (31.7) | 89 (42.8) | ||||||
| 201–350 | 36 (17.6) | 52 (25.4) | 70 (34.2) | ||||||
| 351–500 | 15 (12.9) | 21 (18.1) | 30 (25.9) | ||||||
| >500 | 16 (9.9) | 26 (16.2) | 38 (23.6) | ||||||
| Missing | 1 (4.0) | 4 (16.0) | 6 (24.0) | ||||||
| AIDS defining illness | |||||||||
| Yes | 42 (17.5) | 0.42 (1) | 0.52 | 67 (27.9) | 0.56 (1) | 0.46 | 90 (37.5) | 0.56 (1) | 0.46 |
| No | 155 (15.8) | 251 (25.6) | 343 (34.9) | ||||||
| Substance abuse | |||||||||
| Yes | 22(7.5) | 21.4 (1) | <0.001 | 48 (16.3) | 18.9 (1) | <0.001 | 69 (23.5) | 24.2 (1) | <0.001 |
| No | 175 (18.9) | 270 (29.1) | 364 (39.2) | ||||||
| HIV viral load | |||||||||
| 401–999 | 26 (9.0) | 24.4 (3) | <0.001 | 51 (17.6) | 22.8 (3) | <0.001 | 75 (25.9) | 26.2 (3) | 0.01 |
| 1,000–9,999 | 57 (14.1) | 96 (23.8) | 131 (32.5) | ||||||
| 10,000–99,999 | 74 (20.6) | 114 (31.8) | 156 (43.5) | ||||||
| 100,000 plus | 40 (23.5) | 57 (33.5) | 71 (41.8) | ||||||
| Years on ART | |||||||||
| <10 | 76 (13.1) | 7.57 (1) | 0.006 | 119 (20.5) | 17.7 (1) | <0.001 | 165 (28.4) | 24.0 (1) | <0.001 |
| ≥10 | 121 (18.9) | 199 (31.1) | 268 (41.8) | ||||||
*
Chi-square value (degrees of freedom)