Table 1.
Demographic, anthropometric and clinical data of patients classified according to the extent of coronary lesion
| Variables | Total (n = 59) | Without lesion (n = 18) | Low lesion (n = 17) | Intermediate lesion (n = 17) |
Major lesion (n = 7) |
p-value |
|---|---|---|---|---|---|---|
| Age, years | 60.0 ± 9.0 | 55.0 ± 9.0 | 62.0 ± 9.0 | 63.0 ± 10 | 60.0 ± 7.0 | 0.080 |
| Sex male, % | 54.2 | 44.4 | 58.8 | 64.7 | 42.9 | 0.582 |
| BMI, kg/m2 | 26.82 ± 5.65 | 27.86 ± 4.70 | 25.27 ± 8.52 | 26.92 ± 4.29 | 27.43 ± 1.13 | 0.630 |
| Obesity, % | 20.3 | 33.3 | 17.6 | 17.6 | 0 | 0.133 |
| Dyslipidemia, % | 91.5 | 77.8 | 100.0 | 94.1 | 100.0 | 0.080 |
| Diabetes mellitus, % | 30,5 | 33.3 | 23.5 | 35.3 | 28.6 | 0.884 |
| Hypertension, % | 79.7 | 77.8 | 76.5 | 82.4 | 85.7 | 0.944 |
| Diastolic pressure, mmHg | 84.0 ± 20.0 | 81.0 ± 8.0 | 80.0 ± 24.0 | 90.0 ± 18.0 | 90.0 ± 32.0 | 0.355 |
| Systolic pressure, mmHg | 143.0 ± 26.0 | 137.0 ± 24.0 | 139.0 ± 22.0 | 155.0 ± 32.0 | 141.0 ± 21.0 | 0.187 |
| Alcoholism, % | 18.6 | 27.8 | 17.6 | 5.9 | 28.6 | 0.350 |
| Smoking, % | 22.0 | 27.8 | 17.6 | 17.6 | 28.6 | 0.825 |
| Physical activity, % | 47.5 | 50.0 | 58.8 | 35.3 | 42.9 | 0.573 |
| Biochemical Analyses | ||||||
| Glucose, mmol/l | 5.16 (3.72–21.87) | 4.75 (3.89–14.26) | 4.88 (3.75–11.04) | 5.55 (3.72–21.87) | 5.94 (4.44–13.04) | 0.443 |
| Total cholesterol, mmol/l | 4.61 (2.95–7.85) | 4.36 (3.08–6.50) | 4.51 (3.19–6.89) | 5.05 (2.95–7.85) | 4.61(3.65–7.02) | 0.555 |
| HDL-cholesterol, mmol/l | 0.92 (0.41–1.45) | 0.95 (0.57–1.45) | 0.93 (0.54–1.30) | 0.91 (0.41–1.32) | 0.83 (0.62–1.40) | 0.669 |
| LDL-cholesterol, mmol/l | 2.68 (1.21–5.74) | 2.38(1.49–4.57) | 2.63(1.21–5.00) | 3.26 (1.21–5.74) | 2.89 (1.93–5.27) | 0.419 |
| Triglycerides, mmol/l | 1.62 (0.75–9.47) | 1.63 (0.79–6.94) | 2.25(0.86–6.96) | 1.62(0.75–9.47) | 1.45 (0.85–3.24) | 0.612 |
| ALT, μKat/l | 0.43 (0.17–2.19) | 0.38 (0.17–1.57) | 0.43 (0.25–1.04) | 0.33 (0.17–2.19) | 0.60 (0.25–1.45) | 0.723 |
| AST, μKat/l | 0.52 (0.25–1.57) | 0.52 (0.25–1.49) | 0.43 (0.25–0.95) | 0.52 (0.25–1.57) | 0.60 (0.25–1.57) | 0.546 |
| Ureia, mmol/l | 5.85 (3.34–10.35) | 5.93 (3.34–9.52) | 5.68 (4.31–9.85) | 5.93(3.37–10.35) | 5.85 (4.84–6.35) | 0.693 |
| Creatinine, μmol/l | 79.56 (17.68–141.44) | 79.56 (53.04–141.44) | 79.56(53.04–123.76) | 88.40 (53.04–106.08) | 70.72 (17.68–106.08) | 0.323 |
| Uric acid, mmol/l | 0.29 (0.11–0.52) | 0.27(0.16–0.52) | 0.28 (0.11–0.43) | 0.29 (0.11–0.43) | 0.33 (0.14–0.37) | 0.965 |
Data are presented as mean ± standard deviation for parametric samples and as median (interquartile range) for non-parametric samples. Categorical variables were compared by Chi-square test. Parametric analysis was performed by ANOVA way. Non-parametric samples were performed by Kruskal-Wallis test. P-values < 0.05 were considered statistically significant in all statistical test. BMI body mass index, HDL-cholesterol high density lipoprotein, LDL-cholesterol low density lipoprotein, AST aspartate aminotransferase, ALT alanine transaminase