Table 2.
Serum fatty acid concentration according to the extent of coronary lesion
| Fatty acids (%) | Total (n = 59) | Without lesion (n = 18) | Low lesion (n = 17) | Intermediate lesion (n = 17) | Major lesion (n = 7) | p-value |
|---|---|---|---|---|---|---|
| SFA | 44.12 ± 3.85 | 44.70 ± 4.18 | 43.79 ± 4.46 | 43.93 ± 2.74 | 43.93 ± 4.40 | 0.904 |
| Myristic (C14:0) | 0.89 ± 0.30 | 0.94 ± 0.36 | 0.91 ± 0.26 | 0.87 ± 0.31 | 0.80 ± 0.19 | 0.756 |
| Palmitic (C16:0) | 30.83 ± 3.07 | 31.40 ± 2.95 | 30.61 ± 3.15 | 30.52 ± 2.80 | 30.63 ± 4.22 | 0.830 |
| Stearic (C18:0) | 12.40 ± 1.89 | 12.36 ± 2.15 | 12.27 ± 2.10 | 12.54 ± 1.70 | 12.50 ± 1.30 | 0.979 |
| MUFA | 24.87 ± 3.10 | 23.66 ± 2.88 | 25.97 ± 2.84a | 25.77 ± 2.96b | 23.14 ± 3.35 | 0.032 |
| Palmitoleic (C16:1) | 2.55 ± 0.75 | 2.41 ± 0.62 | 2.73 ± .63 | 2.56 ± 0.89 | 2.47 ± 0.98 | 0.658 |
| Oleic (C18:1) | 22.32 ± 2.77 | 21.25 ± 2.54 | 23.24 ± 2.48c | 23.22 ± 2.73d | 20.66 ± 2.89 | 0.027 |
| PUFA | 31.01 ± 4.78 | 31.65 ± 4.46 | 30.24 ± 5.37 | 30.30 ± 3.99 | 32.94 ± 6.01 | 0.529 |
| n-6 | 26.77 ± 4.29 | 27.26 ± 3.66 | 25.96 ± 5.13 | 26.46 ± 3.54 | 28.26 ± 5.53 | 0.628 |
| Linoleic (C18:2) | 18.06 ± 3.84 | 18.64 ± 3.29 | 17.23 ± 4.35 | 18.10 ± 3.30 | 18.47 ± 5.39 | 0.742 |
| Arachidonic (C20:4) | 8.71 ± 2.37 | 8.62 ± 1.73 | 8.73 ± 2.47 | 8.36 ± 2.20 | 9.78 ± 3.89 | 0.620 |
| n-3 | 4.23 ± 1.17 | 4.38 ± 1.56 | 4.29 ± 1.02 | 3.84 ± 0.86 | 4.68 ± 0.91 | 0.363 |
| a-linolenic (C18:3) | 0.54 ± 0.20 | 0.56 ± 0.20 | 0.53 ± 0.21 | 0.52 ± 0.16 | 0.57 ± 0.31 | 0.916 |
| EPA (C20:5) | 0.46 ± 0.18 | 0.53 ± 0.24 | 0.42 ± 0.15 | 0.43 ± 0.16 | 0.52 ± 0.11 | 0.223 |
| DPA (C22:5) | 0.83 ± 0.23 | 0.83 ± 0.21 | 0.86 ± 0.17 | 0.80 ± 0.28 | 0.85 ± 0.33 | 0.891 |
| DHA (C22:6) | 2.39 ± 0.93 | 2.46 ± 1.26 | 2.48 ± 0.82 | 2.10 ± 0.67 | 2.74 ± 0.73 | 0.410 |
| n-6/n-3 | 6.77 ± 2.12 | 6.80 ± 1.93 | 6.61 ± 2.96 | 7.14 ± 1.63 | 6.16 ± 1.29 | 0.765 |
| SCD16 | 0.08 ± 0.02 | 0.08 ± 0.02 | 0.09 ± 0.02 | 0.08 ± 0.02 | 0.08 ± 0.03 | 0.398 |
| SCD18 | 1.85 ± 0.40 | 1.77 ± 0.38 | 1.95 ± 0.38 | 1.90 ± 0.45 | 1.68 ± 0.36 | 0.376 |
Data are presented as mean ± standard deviation. Comparisons were performed by ANOVA way test followed by test t between pairs. P-values < 0.05 were considered statistically significant for all statistical test
EPA, eicosapentaenoic, DHA docosahexaenoic, DPA docosapentaenoic SFA saturated fatty acid, MUFA monounsaturated fatty acid, PUFA polyunsaturated fatty acid, n6 omega-6, n3 omega-3, SCD16 stearoyl-CoA-Desaturase 16, SCD18, stearoyl-CoA-Desaturase 18
a p = 0.023 for comparison between low lesion vs. without lesion groups by test t
b p = 0.040 for comparison between intermediate lesion vs. without lesion groups by test t
c p = 0.025 comparison between low lesion vs. without lesion groups by test t
d p = 0.034 for comparison between intermediate lesion vs. without lesion groups by test t