Fig. 3.

Distance estimation of blocking effects on neuronal firing by LGN- and V1-lidocaine infusion. a Examples of SR changes caused by 1 μl lidocaine infusion in LGN, which were measured at the distances of 1.2 mm (left) and 1.5 mm (right) from infusion sites; drugs were applied during 0–2 min (indicated by thick bars); insets at top, representative SRs (time points of firing are indicated by vertical bars) before and after drug infusion. b Summary of all experiments shown in (a) (n = 13 and 10 for recordings at 1.2 mm and 1.5 mm, respectively); data were normalized to mean SRs measured within 0–5 min before drug application. c and d Same as (a) and (b), but for V1-lidocaine infusion, in which 0.4 μl lidocaine was applied for 2 min and SR recordings were obtained at the distances of 0.8 mm and 1.0 mm from infusion sites (n = 10 and 9 for recordings at 0.8 mm and 1.0 mm, respectively)