Table 2.
General features of the studies included
| Studies | Type of study | No of patients with low dose ASA (n) | No of patients with high dose ASA (n) | Total no of patients (n) | Type of P2Y12 inhibitor used |
|---|---|---|---|---|---|
| GHOST [10] | observational | 313 | 2507 | 2820 | clopidogrel |
| CURRENT OASIS 7 [11] | RCT | 3371 | 3502 | 6873 | clopidogrel |
| CURE [4, 12] | RCT | 8429 | 4110 | 12,539 | clopidogrel |
| HORIZONS-AMI [13] | RCT | 2289 | 562 | 2851 | clopidogrel |
| Total no of patients (n) | 14,402 | 10,681 | 25,083 |
Only female patients were included from trial CURRENT OASIS 7 in order to avoid the influence of this trial on the results of this analysis
Abbreviations: ASA aspirin, RCT randomized controlled trials