Table 2.
Echocardiographic structural data
| SHR (n = 16) | SHR-APO (n = 16) | SHR-DM (n = 13) | SHR-DM-APO (n = 14) | |
|---|---|---|---|---|
| LVDD/BW (mm/kg) | 19.5 ± 1.87 | 20.4 ± 2.27 | 26.2 ± 5.04* | 26.6 ± 4.71# |
| LA/BW (mm/kg) | 17.3 ± 2.06 | 17.3 ± 2.14 | 20.5 ± 3.97* | 21.1 ± 3.23# |
| PWT (mm) | 1.69 ± 0.17 | 1.71 ± 0.19 | 1.63 ± 0.17 | 1.55 ± 0.16# |
| RWT | 0.46 ± 0.06 | 0.45 ± 0.07 | 0.47 ± 0.07 | 0.46 ± 0.07 |
| LVM/BW (g/kg) | 2.34 ± 0.37 | 2.54 ± 0.57 | 2.89 ± 0.64* | 2.70 ± 0.59 |
Data are expressed as mean ± standard deviation
SHR spontaneously hypertensive rats; SHR-APO SHR treated with apocynin; SHR-DM diabetic SHR; SHR-DM-APO diabetic SHR treated with apocynin; LVDD left ventricular (LV) diastolic diameter; BW body weight; LA left atrial diameter; PWT LV posterior wall thickness; RWT relative wall thickness; LVM LV mass
Two-factor ANOVA; * p < 0.05 vs SHR; # p < 0.05 vs SHR-APO