Table 3.
Relative expression of genes for superoxide dismutase isoforms, catalase, glutathione peroxidase 1 and 4, endothelial and inducible nitric oxide synthases, and NADPH oxidase components in brain blood vessels
| Experimental | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| group | Cu/Zn SOD | Mn SOD | EC SOD | CAT | GPx1 | GPx4 | eNOS | iNOS | p47phox | gp91phox |
| LS | 1.09 ± 0.18 | 0.9 ± 0.19 | 0.60 ± 0.20 | 0.87 ± 0.11 | 1.23 ± 0.38 | 0.82 ± 0.17 | 0.589 ± 0.26 | 2.56 ± 1.49 | 0.675 ± 0.28 | 0.72 ± 0.25 |
| HS | 0.97 ± 0.14 | 0.79 ± 0.16 | 0.51 ± 0.11 | 0.74 ± 0.19 | 0.92 ± 0.22 | 0.64 ± 0.06* | 0.43 ± 0.45 | 0.47 ± 0.33* | 0.74 ± 0.33 | 0.54 ± 0.25 |
| P value | 0.226 | 0.138 | 0.295 | 0.181 | 0.096 | 0.041 | 0.516 | 0.004 | 0.657 | 0.178 |
Superoxide dismutase isoforms: Cu/Zn SOD, Mn SOD and EC SOD; catalase: CAT; glutathione peroxidase 1 and 4: GPx1, GPx4; endothelial nitric oxide synthase: eNOS; inducible nitric oxide synthase: iNOS; NADPH oxidase components: p47phox and gp91phox. Data are presented as means ± SD. * P < 0.05 LS vs. HS diet; LS, low salt; HS, high salt.